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Cells in the non-uniform magnetic world: how cells respond to high-gradient magnetic fields
- 1.0492453 - FZÚ 2019 RIV GB eng J - Journal Article
Zablotskyy, Vitaliy A. - Polyakova, Tetyana - Dejneka, Alexandr
Cells in the non-uniform magnetic world: how cells respond to high-gradient magnetic fields.
BioEssays. Roč. 40, č. 8 (2018), s. 1-10, č. článku 1800017. ISSN 0265-9247. E-ISSN 1521-1878
Institutional support: RVO:68378271
Keywords : cell differentiation * cell fate * cell signaling * intracellular forces * magnetic fields * magnetic gradient
OECD category: Biophysics
Impact factor: 4.396, year: 2018
Imagine cells that live in a high-gradient magnetic field (HGMF). Through what mechanisms do the cells sense a non-uniform magnetic field and how such a field changes the cell fate? We show that magnetic forces generated by HGMFs can be comparable to intracellular forces and therefore may be capable of altering the functionality of an individual cell and tissues in unprecedented ways. We identify the cellular effectors of such fields and propose novel routes in cell biology predicting new biological effects such as magnetic control of cell-to-cell communication and vesicle transport, magnetic control of intracellular ROS levels, magnetically induced differentiation of stem cells, magnetically assisted cell division, or prevention of cells from dividing.
Permanent Link: http://hdl.handle.net/11104/0285988
Number of the records: 1