The effect of Syphacia muris on nutrient digestibility in laboratory rats

0459366 - FGÚ 2017 RIV GB eng J - Journal Article
Plachý, V. - Litvinec, Andrej - Langrová, I. - Horáková, B. - Sloup, V. - Jankovská, I. - Vadlejch, J. - Čadková, Z. - Borkovcová, M.
The effect of Syphacia muris on nutrient digestibility in laboratory rats.
Laboratory Animals. Roč. 50, č. 1 (2016), s. 39-44. ISSN 0023-6772. E-ISSN 1758-1117
Institutional support: RVO:67985823
Keywords : laboratory rat * Syphacia muris * infection * nutrient * digestibility
Subject RIV: EG - Zoology
Impact factor: 1.532, year: 2016

This study was carried out to investigate how pinworm infection in rats affects nutrient digestibility in the hosts. Twenty-four male outbred Wistar rats were randomly divided into two groups of 12 rats each. The rats from the first group (GI) were kept in cages with bedding containing pinworm eggs, and the second (control) group (GII) were kept in a separate room in clean, uncontaminated filter-top cages. The animals were put into individual metabolic cages later. Metabolic trials lasted five days and records of animal weight, food ingestion, and faecal weight were taken daily. Based on laboratory analysis of the feed and faecal nutrient content, digestibility values were determined. On day 15 of the experiment, the animals were euthanized. Although Syphacia muris were found in all rats from the GI group, animals exhibited no clinical signs. In our experiment, S. muris infection reduced the overall digestibility of all measured nutrients (P<0.01). The most significant differences in digestibility were observed in the case of crude fibre and mineral matter (P<0.01).
Permanent Link: http://hdl.handle.net/11104/0259576