0452542 - ARÚ 2016 RIV GB eng J - Journal Article
Podgorná, Eliška - Diallo, I. - Vangenot, Ch. - Sanchez-Mazas, A. - Sabbagh, A. - Černý, Viktor - Poloni, E. S.
Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.
BMC Evolutionary Biology. Roč. 15, č. 263 (2015). ISSN 1471-2148. E-ISSN 1471-2148
R&D Projects: GA ČR GA13-37998S
Institutional support: RVO:67985912
Keywords : NAT2 * acetylation polymorphism * African Sahel * pastoral nomads * subsistence mode * ecoregion * natural selection
Subject RIV: AC - Archeology, Anthropology, Ethnology
Impact factor: 3.406, year: 2015
http://www.biomedcentral.com/1471-2148/15/263

The main shift in subsistence strategies is associated with dietary changes in Neolithic and subsequent population differentiations as far as the food-production lifestyle concerns. However, we show in this study that the genetic structure of human populations living in the African Sahel corresponds more strongly with ecoregions than to subsistence strategies. Our results thus suggest a possible independent influence of both the dietary habits associated with subsistence modes and the chemical environment associated with climatic zones and biomes on the evolution of NAT2 diversity in sub-Saharan African populations.
Permanent Link: http://hdl.handle.net/11104/0253564