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Update on the role of spinal cord TRPV1 receptors in pain modulation
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SYSNO ASEP 0428034 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Update on the role of spinal cord TRPV1 receptors in pain modulation Author(s) Špicarová, Diana (FGU-C) RID, ORCID
Nerandžič, Vladimír (FGU-C)
Paleček, Jiří (FGU-C) RID, ORCIDSource Title Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 63, Suppl.1 (2014), S225-S236Number of pages 12 s. Language eng - English Country CZ - Czech Republic Keywords hyperalgesia ; capsaicin ; TRPV1 ; Spinal cord Subject RIV FH - Neurology R&D Projects GA305/09/1228 GA ČR - Czech Science Foundation (CSF) LH12058 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GBP304/12/G069 GA ČR - Czech Science Foundation (CSF) GPP303/12/P510 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 UT WOS 000332073100019 EID SCOPUS 84897589790 Annotation The structure, expression and function of the transient receptor potential vanilloid 1 (TRPV1) receptor were intensively studied since the cloning in 1997 and TRPV1 receptors are now considered to act as transducers and molecular integrators of nociceptive stimuli in the periphery. In contrast, spinal TRPV1 receptors were studied less extensively and their role in pain modulation is still not fully understood. This short review is a follow up on our previous summary in this area (Spicarova and Palecek 2008) Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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