Synthesis, thermal, spectral and biological properties of zinc(II) 4-hydroxybenzoate complexes

0427446 - ÚMCH 2015 RIV HU eng J - Journal Article
Homzová, K. - Györyová, K. - Bujdošová, Z. - Hudecová, D. - Ganajová, M. - Vargová, Z. - Kovářová, Jana
Synthesis, thermal, spectral and biological properties of zinc(II) 4-hydroxybenzoate complexes.
Journal of Thermal Analysis and Calorimetry. Roč. 116, č. 1 (2014), s. 77-91. ISSN 1388-6150. E-ISSN 1588-2926
Institutional support: RVO:61389013
Keywords : zinc * 4-hydroxybenzoate * thermal
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.042, year: 2014

New zinc(II) 4-hydroxybenzoate complex compounds with general formula [Zn(4-OHbenz)2Ln]·xH2O, where 4-OHbenz = 4-hydroxybenzoate; L = isonicotinamide, N-methylnicotinamide, N,N-diethylnicotinamide, thiourea, urea, phenazone, theophylline, methyl-3-pyridylcarbamate; n = 2, 3; x = 0–3, 5, were synthesized and characterised by elemental analysis, thermal analysis and IR spectroscopy. The thermal behaviour of the prepared compounds was studied by TG/DTG and DTA methods in argon atmosphere. The thermal decomposition of hydrated compounds started with dehydration. During the thermal decomposition, organic ligand, carbon monoxide, carbon dioxide and phenol were evolved. The final solid product of the thermal decomposition was zinc or zinc oxide. The volatile gaseous product, solid intermediate products and the final product of thermal decomposition were identified by IR spectroscopy, mass spectrometry, qualitative chemical analyses and X-ray powder diffraction method. The antimicrobial activity of zinc(II) carboxylate compounds was tested against various strains of bacteria, yeasts and filamentous fungi (S. aureus, E. coli, C. parapsilosis, R. oryzae, A. alternata, M. gypseum). The presence of zinc in complexes led to the increase in their antimicrobial activity in comparison with free 4-hydroxybenzoic acid.
Permanent Link: http://hdl.handle.net/11104/0235084