Transgenní potkani kmene SHR/Ola exprimující shRNA (short hairpin RNA) komplementární se sekvencí Dazl (deleted in azoospermia-like) genu pod kontrolou Pol III promotoru U6. V důsledku RNA interference (RNAi) mají sníženou expresi Dazl genu

0339733 - FGÚ 2010 RIV CZ cze L - Prototype, f. module
Landa, Vladimír - Zídek, Václav - Pravenec, Michal
Transgenní potkani kmene SHR/Ola exprimující shRNA (short hairpin RNA) komplementární se sekvencí Dazl (deleted in azoospermia-like) genu pod kontrolou Pol III promotoru U6. V důsledku RNA interference (RNAi) mají sníženou expresi Dazl genu.
[Strain of trangenic rats SHR/Ola expressing shRNA (short hairpin RNA) complementary to the sequence of the Dazl (deleted in azoospermia-like) gene under control of Pol III U6 promoter. RNA interference (RNAi) results in downregulation of Dazl gene.]
Internal code: SHR/Ola-(U6shRNA-Dazl) ; 2009
Technical parameters: SHR/Ola-(U6shRNA-Dazl)
Economic parameters: 20,000 Kč
R&D Projects: GA MŠMT(CZ) 1M0520
Institutional research plan: CEZ:AV0Z50110509
Keywords : transgenic SHR * Dazl gene * RNA interference
Subject RIV: EB - Genetics ; Molecular Biology

SHR transgenní potkani exprimující shRNA (short hairpin RNA) komplementární se sekvencí Dazl (deleted in azoospermia-like) genu pod kontrolou Pol III U6 promotoru představují model pro in vivo analýzu RNA interference.V důsledku RNA interference (RNAi) mají sníženou expresi Agtr1a genu

Transgenic SHR with the expression of the shRNA (short hairpin RNA) complementary to the sequence of the Dazl (deleted in azoospermia-like) gene under control of Pol III U6 promoter represents a model for the analysis of in vivo RNA interference.RNA interference (RNAi) results in reduced expression of Agtr1a gene
Permanent Link: http://hdl.handle.net/11104/0183173