Number of the records: 1
Variability of Phase Shift Between Blood Pressure and Heart Rate Fluctuations - A Marker of Short-Term Circulation Control
- 1.
SYSNO ASEP 0205681 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Variability of Phase Shift Between Blood Pressure and Heart Rate Fluctuations - A Marker of Short-Term Circulation Control Author(s) Halámek, Josef (UPT-D) RID, ORCID, SAI
Kára, T. (CZ)
Jurák, Pavel (UPT-D) RID, ORCID, SAI
Souček, M. (CZ)
Francis, D. (GB)
Davies, L. C. (GB)
Shen, W. K. (US)
Coats, A. J. (GB)
Novák, M. (CZ)
Nováková, Z. (CZ)
Panovský, R. (CZ)
Toman, J. (CZ)
Šumbera, J. (CZ)
Somers, V. K. (US)Source Title Circulation - ISSN 0009-7322
Roč. 108, č. 3 (2003), s. 292 - 297Number of pages 6 s. Language eng - English Country US - United States Keywords baroreceptors ; respiration ; sudden death Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects GA102/00/1262 GA ČR - Czech Science Foundation (CSF) GA102/02/1339 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z2065902 - UPT-D Annotation Background - We postulated that the variability of the phase shift between blood pressure and heart rate fluctuation near the frequency of 0.10 Hz might be useful in assessing autonomic circulatory control. Methods and Results - We tested this hypothesis in 4 groups of subjects: 28 young, healthy individuals; 13 elderly healthy individuals; patients with coronary heart disease; and 19 patients with a planned or implanted cardioverter-defibrillator (ICD recipients). Data from 5 minutes of free breathing and at 2 different, controlled breathing frequencies (0.10 and 0.33 Hz) were used. Clear differences (P<0.001) in variability of phase were evident between the ICD recipients and all other groups. Furthermore, at a breathing frequency of 0.10 Hz, differences in baroreflex sensitivity (P<0.01) also became evident, even though these differences were not apparent at the 0.33-Hz breathing frequency. Conclusions - The frequency of 0.01 Hz represents a useful and potentially important one for controlled breathing, at which differences in blood pressure - RR interactions become evident. These interactions, whether computed as a variability of phase to define stability of the blood pressure-heart rate interaction or defined as the baroreflex sensitivity to define the gain in heart rate response to blood pressure changes, are significantly different in patients at risk for sudden arrhythmic death. In young versus older healthy individuals, only baroreflex gain is different, with the variability of phase being similar in both groups. The measurements of short-term circulatory control might help in risk stratification for sudden cardiac death. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2004
Number of the records: 1