Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells

Number of the records: 1

1.

SYSNO ASEP	0190933
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells
Author(s)	Zíková, Martina (UMG-J)_RID Sulimenko, Vadym (UMG-J)_{RID, ORCID} Dráber, Pavel (UMG-J)_{RID, ORCID} Dráberová, Eduarda (UMG-J)_{RID, ORCID}
Source Title	FEBS Letters. - : Wiley - ISSN 0014-5793 Roč. 473, č. 1 (2000), s. 19-23
Number of pages	5 s.
Language	eng - English
Country	NL - Netherlands
Subject RIV	EB - Genetics ; Molecular Biology
R&D Projects	GV312/96/K205 GA ČR - Czech Science Foundation (CSF)
	GA204/98/1054 GA ČR - Czech Science Foundation (CSF)
	KSK2038602 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z5052915 - UMG-J
Annotation	Expression of the MA-01 antigen, a thermolabile 210 kDa microtubule-interacting protein, was analysed during neuronal differentiation of P19 embryonal carcinoma cells. The level of MA-01 expression increased approximately ten times during 15 days. The increase started after 2 days of incubation with retinoaic acid and preceded the appearance of neuron-specific tubulin betaIII and neurofilaments. These data indicate that enhanced expression of MA-01 antigen is one of the earliest events occurring in P19 cells during neuronal differentiation.
Workplace	Institute of Molecular Genetics
Contact	Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217
Year of Publishing	2001

Number of the records: 1