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The role of TRPV1 receptors in nociception and pain modulation
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SYSNO ASEP 0091764 Document Type A - Abstract R&D Document Type The record was not marked in the RIV R&D Document Type Není vybrán druh dokumentu Title The role of TRPV1 receptors in nociception and pain modulation Title Úloha TPRV1 receptorů v nocicepci a modulaci bolesti Author(s) Pospíšilová, Eva (FGU-C)
Špicarová, Diana (FGU-C) RID, ORCID
Paleček, Jiří (FGU-C) RID, ORCIDSource Title Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 56, č. 3 (2007), 29P-29PNumber of pages 1 s. Action Fyziologické dny /83./ Event date 06.02.2007-08.02.2007 VEvent location Brno Country CZ - Czech Republic Event type EUR Language eng - English Country CZ - Czech Republic Keywords cpr1 ; TRPV1 ; pain ; dorsal horn Subject RIV FH - Neurology R&D Projects GA305/06/1115 GA ČR - Czech Science Foundation (CSF) GD305/03/H148 GA ČR - Czech Science Foundation (CSF) LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50110509 - FGU-C (2005-2011) Annotation The TRPV1 receptors are on both the peripheral and central branches of nociceptive primary sensory neurons. We studied first the effect of high concentration capsaicin injection in a model of surgical pain to alleviate postincisional allodynia and hyperalgesia and second the role of central TRPV1 receptor using behavioral experiments with intrathecal applocation of receptor antagonist (SB366791) and in vitro recordings of mEPSCs from the superficial dorsal horn neurons in spinal cord slices Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2008
Number of the records: 1