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Improved electro-destruction of bacterial biofilms by coating conductive surfaces with polymers
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SYSNO ASEP 0584110 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Improved electro-destruction of bacterial biofilms by coating conductive surfaces with polymers Author(s) Hoang, Stéphane (UMCH-V)
Zhukouskaya, Hanna (UMCH-V)
Ivanko, Iryna (UMCH-V) RID, ORCID
Svoboda, Jan (UMCH-V) ORCID, RID
Hympánová, M. (CZ)
Marek, J. (CZ)
Soukup, O. (CZ)
Šlouf, Miroslav (UMCH-V) RID, ORCID
Kotek, J. (CZ)
Doris, E. (FR)
Gravel, E. (FR)
Tomšík, Elena (UMCH-V) RID, ORCID
Hrubý, Martin (UMCH-V) RID, ORCIDArticle number 112910 Source Title European Polymer Journal. - : Elsevier - ISSN 0014-3057
Roč. 209, 15 April (2024)Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords bacteria ; biofilm ; polymer Subject RIV CD - Macromolecular Chemistry OECD category Polymer science R&D Projects GA21-01090S GA ČR - Czech Science Foundation (CSF) LUAUS24272 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) EH22_008/0004607 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Limited access Institutional support UMCH-V - RVO:61389013 UT WOS 001218863900001 EID SCOPUS 85187543853 DOI 10.1016/j.eurpolymj.2024.112910 Annotation The formation of biofilm involves cell aggregation and adherence, enveloped by a self-produced extracellular matrix. In the medical domain, biofilm-associated infections pose significant challenges, especially concerning implants. This investigation focuses on enhancing electromediated bacterial biofilm eradication through polymer coatings on the anode. These coatings catalyze reactive oxygen species (ROS) generation or convert hydrophobic coatings to bactericidal hydrophilic polycations, detaching the biofilms that are predominantly polyanionic. The first approach employs a metallized polytetrathienylporphyrin layer with ROS catalytic capability, while the second involves an insoluble hydrophobic polyamide, which, upon oxidation, transforms into a bactericidal hydrolytically degradable polycation. Both approaches show promising efficacy in augmenting electromediated Staphylococcus aureus biofilm destruction. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2025 Electronic address https://www.sciencedirect.com/science/article/pii/S001430572400171X?via%3Dihub
Number of the records: 1