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Ceria-Catalyzed Hydrolytic Cleavage of Sulfonamides
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SYSNO ASEP 0582304 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve SCOPUS Title Ceria-Catalyzed Hydrolytic Cleavage of Sulfonamides Author(s) Henych, Jiří (UACH-T) SAI, RID, ORCID
Šťastný, Martin (UACH-T) SAI, RID
Kříženecká, S. (CZ)
Čundrle, Jan (UACH-T)
Tolasz, Jakub (UACH-T) RID, ORCID, SAI
Dušková, T. (CZ)
Kormunda, M. (CZ)
Ederer, J. (CZ)
Stehlík, Štěpán (FZU-D) RID, ORCID
Ryšánek, P. (CZ)
Neubertová, V. (CZ)
Janoš, P. (CZ)Number of authors 12 Source Title Inorganic Chemistry. - : American Chemical Society - ISSN 0020-1669
Roč. 63, č. 4 (2024), s. 2298-2309Number of pages 12 s. Language eng - English Country US - United States Keywords Bond cleavage ; Chemical reactions ; Hydrolysis ; Oxides ; Reaction products Subject RIV CA - Inorganic Chemistry OECD category Inorganic and nuclear chemistry Subject RIV - cooperation Institute of Physics - Physical ; Theoretical Chemistry R&D Projects TH76030002 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) LM2023066 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support UACH-T - RVO:61388980 ; FZU-D - RVO:68378271 EID SCOPUS 85183016420 DOI 10.1021/acs.inorgchem.3c04367 Annotation Nanoceria is a promising nanomaterial for the catalytic hydrolysis of a wide variety of substances. In this study, it was experimentally demonstrated for the first time that CeO2 nanostructures show extraordinary reactivity toward sulfonamide drugs (sulfadimethoxine, sulfamerazine, and sulfapyridine) in aqueous solution without any illumination, activation, or pH adjustment. Hydrolytic cleavage of various bonds, including S-N, C-N, and C-S, was proposed as the main reaction mechanism and was indicated by the formation of various reaction products, namely, sulfanilic acid, sulfanilamide, and aniline, which were identified by HPLC-DAD, LC-MS/MS, and NMR spectroscopy. The kinetics and efficiency of the ceria-catalyzed hydrolytic cleavage were dependent on the structure of the sulfonamide molecule and physicochemical properties of Nanoceria prepared by three different precipitation methods. However, in general, all three ceria samples were able to cleave SA drugs tested, proving the robust and unique surface reactivity toward these compounds inherent to cerium dioxide. The demonstrated reactivity of CeO2 to molecules containing sulfonamide or even sulfonyl (and similar) functional groups may be significant for both heterogeneous catalysis and environmentally important degradation reactions. Workplace Institute of Inorganic Chemistry Contact Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931 Year of Publishing 2025 Electronic address https://hdl.handle.net/11104/0350420
Number of the records: 1