Spectral, structural, and pharmacological studies of perillaldehyde and myrtenal based benzohydrazides

0561802 - FZÚ 2024 RIV NL eng J - Journal Article
Garberová, M. - Potočňák, I. - Tvrdoňová, M. - Bago-Pilátová, M. - Bekešová, S. - Kudličková, A. - Samoľová, Erika - Kešeľáková, A. - Elečko, J. - Vilková, M.
Spectral, structural, and pharmacological studies of perillaldehyde and myrtenal based benzohydrazides.
Journal of Molecular Structure. Roč. 1271, Jan (2023), č. článku 134112. ISSN 0022-2860. E-ISSN 1872-8014
Institutional support: RVO:68378271
Keywords : hydrazone * 1H, 13C, and 15N NMR * X-ray analysis * HR-MS * antitumor activity
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 3.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.molstruc.2022.134112

N-Acylhydrazones have been an interesting scaffold due to their diverse biological activities toward different therapeutic targets. We synthesized seven new N'-[(E)-[(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methylidene]benzohydrazides as well as seven new N'-[(E)-{6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl}methylidene]benzohydrazides. The structure of synthesized hydrazides has been studied by using X- ray analysis, FT-IR, NMR, and HRMS spectra.
Permanent Link: https://hdl.handle.net/11104/0341680