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Importing genetically altered animals: ensuring quality
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SYSNO ASEP 0555859 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Importing genetically altered animals: ensuring quality Author(s) Birling, M.C. (FR)
Fray, M. (GB)
Kašpárek, Petr (UMG-J)
Kopkanová, Jana (UMG-J)
Massimi, M. (IT)
Matteoni, R. (IT)
Montoliu, L. (ES)
Nutter, L.M.J. (CA)
Raspa, M. (IT)
Rozman, Jan (UMG-J)
Ryder, E. (GB)
Scavizzi, F. (IT)
Voikar, V. (FI)
Wells, S. (GB)
Pavlovic, G. (FR)
Teboul, L. (GB)Number of authors 16 Source Title Mammalian Genome. - : Springer - ISSN 0938-8990
Roč. 33, č. 1 (2022), s. 100-107Number of pages 8 s. Publication form Online - E Language eng - English Country US - United States Keywords cre recombinase ; mouse ; mice ; reproducibility ; expression ; microbiota ; rodent ; cells ; gene ; rat Subject RIV EB - Genetics ; Molecular Biology OECD category Biochemistry and molecular biology R&D Projects LM2018126 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) ED2.1.00/19.0395 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) EF18_046/0015861 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Research Infrastructure CCP II - 90126 - Ústav molekulární genetiky AV ČR, v. v. i. Method of publishing Open access Institutional support UMG-J - RVO:68378050 UT WOS 000756487900001 EID SCOPUS 85115200134 DOI 10.1007/s00335-021-09908-x Annotation The reproducibility of research using laboratory animals requires reliable management of their quality, in particular of their genetics, health and environment, all of which contribute to their phenotypes. The point at which these biological materials are transferred between researchers is particularly sensitive, as it may result in a loss of integrity of the animals and/or their documentation. Here, we describe the various aspects of laboratory animal quality that should be confirmed when sharing rodent research models. We also discuss how repositories of biological materials support the scientific community to ensure the continuity of the quality of laboratory animals. Both the concept of quality and the role of repositories themselves extend to all exchanges of biological materials and all networks that support the sharing of these reagents. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2024 Electronic address https://link.springer.com/article/10.1007/s00335-021-09908-x
Number of the records: 1