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Novel LDPE/vermiculite/ciclopiroxolamine hybrid nanocomposites: Structure, surface properties, and antifungal activity
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SYSNO ASEP 0544969 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Novel LDPE/vermiculite/ciclopiroxolamine hybrid nanocomposites: Structure, surface properties, and antifungal activity Author(s) Holešová, S. (CZ)
Čech Barabaszová, K. (CZ)
Hundáková, M. (CZ)
Plevová, Eva (UGN-S) RID, ORCID
Kalendová, A. (CZ)Number of authors 5 Article number 50232 Source Title Journal of Applied Polymer Science. - : Wiley - ISSN 0021-8995
Roč. 138, č. 16 (2021)Number of pages 10 s. Publication form Online - E Language eng - English Country US - United States Keywords nanocomposites ; vermiculite ; ciclopiroxolamine ; polyethylene Subject RIV CB - Analytical Chemistry, Separation OECD category Analytical chemistry Method of publishing Limited access Institutional support UGN-S - RVO:68145535 UT WOS 000585313600001 EID SCOPUS 85096811786 DOI 10.1002/app.50232 Annotation The increasing number of indwelling medical materials and devices are connected with infections caused by yeast, especially Candida albicans. This pathogen produces undesirable biofilms on synthetic materials. Since antimicrobial polymer nanocomposites present one of the promising possibility of reduction of such biofilms, therefore this study is focused on developing nanocomposite based on low density polyethylene (LDPE) with clay mineral vermiculite as an active carrier for antifungal compound. The set of LDPE/vermiculite nanocomposite with increasing amount of antifungal nanofiller was prepared. As antifungal agent was selected generally used active substance ciclopiroxolamine. The structure of all prepared samples was studied by X-ray diffraction analysis and Fourier transforms infrared spectroscopy. Further thermal properties of polyethylene/clay nanocomposites were investigated by thermogravimetric analysis and the surface properties were evaluated by light optical microscopy, scanning electron microscopy and atomic force microscopy. From mentioned characteristics, we conclude that presence of nanofiller in LDPE primarily causes shift of thermal degradation to higher temperatures and increasing of microhardness. All prepared LDPE nanocomposites possess an excellent and prolonged antifungal activity against Candida albicans. Workplace Institute of Geonics Contact Lucie Gurková, lucie.gurkova@ugn.cas.cz, Tel.: 596 979 354 Year of Publishing 2022 Electronic address https://onlinelibrary.wiley.com/doi/full/10.1002/app.50232
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