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Nanostructured materials for artificial tissue replacements
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SYSNO ASEP 0541362 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Nanostructured materials for artificial tissue replacements Author(s) Pryjmakova, J. (CZ)
Kaimlová, M. (CZ)
Hubáček, Tomáš (BC-A) RID
Švorčík, V. (CZ)
Siegel, J. (CZ)Number of authors 5 Article number 2521 Source Title International Journal of Molecular Sciences. - : MDPI
Roč. 21, č. 7 (2020)Number of pages 29 s. Language eng - English Country CH - Switzerland Keywords nanomaterials ; tissue engineering ; biologic properties ; mechanical properties ; antibacterial effects Subject RIV EB - Genetics ; Molecular Biology OECD category Biochemistry and molecular biology R&D Projects GA17-10907S GA ČR - Czech Science Foundation (CSF) Method of publishing Open access Institutional support BC-A - RVO:60077344 UT WOS 000535574200263 EID SCOPUS 85083023328 DOI 10.3390/ijms21072521 Annotation This paper review current trends in applications of nanomaterials in tissue engineering. Nanomaterials applicable in this area can be divided into two groups: organic and inorganic. Organic nanomaterials are especially used for the preparation of highly porous scaffolds for cell cultivation and are represented by polymeric nanofibers. Inorganic nanomaterials are implemented as they stand or dispersed in matrices promoting their functional properties while preserving high level of biocompatibility. They are used in various forms (e.g., nano- particles,tubes andfibers)-and when forming the composites with organic matrices-are able to enhance many resulting properties (biologic, mechanical, electrical and/or antibacterial). For this reason, this contribution points especially to such type of composite nanomaterials. Basic information on classification, properties and application potential of single nanostructures, as well as complex scaffolds suitable for 3D tissues reconstruction is provided. Examples of practical usage of these structures are demonstrated on cartilage, bone, neural, cardiac and skin tissue regeneration and replacements. Nanomaterials open up new ways of treatments in almost all areas of current tissue regeneration, especially in tissue support or cell proliferation and growth. They significantly promote tissue rebuilding by direct replacement of damaged tissues. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2021 Electronic address https://doi.org/10.3390/ijms21072521
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