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Chitosan-glucan complex hollow fibers reinforced collagen wound dressing embedded with aloe vera. Part I: Preparation and characterization
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SYSNO ASEP 0532392 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Chitosan-glucan complex hollow fibers reinforced collagen wound dressing embedded with aloe vera. Part I: Preparation and characterization Author(s) Abdel-Mohsen, A. M. (CZ)
Abdel-Rahman, R. M. (CZ)
Kuběna, Ivo (UFM-A) RID, ORCID
Kobera, Libor (UMCH-V) RID, ORCID
Spotz, Z. (CZ)
Zboncak, M. (CZ)
Přikryl, R. (CZ)
Brus, Jiří (UMCH-V) RID, ORCID
Jančar, J. (CZ)Number of authors 9 Article number 115708 Source Title Carbohydrate Polymers. - : Elsevier - ISSN 0144-8617
Roč. 230, FEB (2020)Number of pages 15 s. Language eng - English Country GB - United Kingdom Keywords Chitosan-glucan ; Hollow fiber ; Collagen ; Aloe vera ; Degradation ; Release properties ; Wound dressing Subject RIV CD - Macromolecular Chemistry OECD category Polymer science Subject RIV - cooperation Institute of Macromolecular Chemistry - Macromolecular Chemistry Method of publishing Limited access Institutional support UFM-A - RVO:68081723 ; UMCH-V - RVO:61389013 UT WOS 000504402300017 EID SCOPUS 85076496931 DOI 10.1016/j.carbpol.2019.115708 Annotation Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 +/- 250 nm) and outer fiber diameter of (2.5 +/- 0.5 mu m). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers. Workplace Institute of Physics of Materials Contact Yvonna Šrámková, sramkova@ipm.cz, Tel.: 532 290 485 Year of Publishing 2021 Electronic address https://www.sciencedirect.com/science/article/pii/S0144861719313761?via%3Dihub
Number of the records: 1