Number of the records: 1
Nanomaterials in Biomedical research
- 1.0491794 - ÚEM 2019 RIV CZ eng M - Monography Chapter
Krulová, Magdaléna - Hájková, Michaela - Javorková, Eliška
Immunosuppressive Effects of Mesenchymal Stem Cells Applied on Nanofiber Scaffolds in Combination with a Local Immunosuppression in a Model of Skin Transplantation.
Nanomaterials in Biomedical research. Praha 3: Proxima Tisk, s.r.o., 2017 - (Caraglia, M.), s. 101-105. ISBN 978-80-906655-5-2
R&D Projects: GA MŠMT(CZ) LO1309
Institutional support: RVO:68378041
Keywords : nanomaterials * cyclosporine A * transplantation * mesenchymal stem cells
OECD category: Cell biology
Allogeneic skin transplantation is usually associated with deleterious inflammatory reaction and requires administration of high doses of immunosuppressive drugs. Mesenchymal stem cells due to their regenerative and immunosuppressive properties offer a great potential for the cell therapy. We confirmed that locally applied mesenchymal stem cells in combination with cyclosporine A induce a switch in macrophage to a phenotype that reduce the local inflammatory reaction and support wound healing
Permanent Link: http://hdl.handle.net/11104/0285825
Number of the records: 1