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Development of thiol-ene-based enzymatic microreactor array for drug metabolism study
- 1.0475707 - ÚIACH 2018 CZ eng A - Abstract
Přikryl, Jan - Lafleur, J. P. - Foret, František - Ertl, P.
Development of thiol-ene-based enzymatic microreactor array for drug metabolism study.
HPLC 2017. Final Program. Praha: Czech-In s. r. o., 2017. s. 264-265.
[International symposium on high performance liquid phase separations and related techniques /45./. 18.06.2017-22.06.2017, Praha]
R&D Projects: GA ČR(CZ) GBP206/12/G014
Grant - others:GA AV ČR(CZ) MSM200311601
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:68081715
Keywords : microreactor * drug metabolism * thiol-enes * OSTE
Subject RIV: CB - Analytical Chemistry, Separation
In this work, we report on the design and fabrication of microfluidic device and monolithic column based on thiol-ene click chemistry. The device was used to mimic drug metabolism in a lab thanks to immobilized liver microsomes.
Permanent Link: http://hdl.handle.net/11104/0272355
File Download Size Commentary Version Access HPLC_2017_poster_Prikryl_06.pdf 0 1.1 MB Other require 0475707.pdf 0 4 MB Other open-access
Number of the records: 1