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Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2(high) Breast Cancer
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SYSNO ASEP 0473778 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2(high) Breast Cancer Author(s) Rohlenová, Kateřina (BTO-N) ORCID, RID
Sachaphibulkij, K. (AU)
Stursa, J. (CZ)
Bezawork-Geleta, A. (AU)
Blecha, Jan (BTO-N)
Endaya, B. (AU)
Werner, L. (CZ)
Černý, Jiří (BTO-N) RID, ORCID
Zobalová, Renata (BTO-N) RID
Goodwin, J. (AU)
Špaček, Tomáš (FGU-C) RID, ORCID
Pesdar, E.A. (AU)
Yan, B. (AU)
Nguyen, M.N. (AU)
Vondrusová, Magdaléna (BTO-N) RID
Sobol, Margaryta (UMG-J) RID
Ježek, Petr (FGU-C) RID, ORCID
Hozák, Pavel (UMG-J) RID, ORCID
Truksa, Jaroslav (BTO-N) RID, ORCID
Rohlena, Jakub (BTO-N) RID, ORCID
Dong, L.F. (AU)
Neužil, Jiří (BTO-N) RIDSource Title Antioxidants & Redox Signaling. - : Mary Ann Liebert - ISSN 1523-0864
Roč. 26, č. 2 (2017), s. 84-103Number of pages 20 s. Language eng - English Country US - United States Keywords mitochondrially targeted tamoxifen ; HER2 ; respirasome Subject RIV EB - Genetics ; Molecular Biology OECD category Biochemistry and molecular biology Subject RIV - cooperation Institute of Physiology - Genetics ; Molecular Biology
Institute of Molecular Genetics - Genetics ; Molecular BiologyR&D Projects GA16-12719S GA ČR - Czech Science Foundation (CSF) GA16-22823S GA ČR - Czech Science Foundation (CSF) GA13-28830S GA ČR - Czech Science Foundation (CSF) GA16-12816S GA ČR - Czech Science Foundation (CSF) TE01020118 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) FR-TI3/588 GA MPO - Ministry of Industry and Trade (MPO) LQ1604 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) ED1.1.00/02.0109 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support BTO-N - RVO:86652036 ; FGU-C - RVO:67985823 ; UMG-J - RVO:68378050 UT WOS 000391823300003 EID SCOPUS 85008884183 DOI 10.1089/ars.2016.6677 Annotation Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain (ETC) is a viable strategy to eliminate Her2(high) disease. Workplace Institute of Biotechnology Contact Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Year of Publishing 2018
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