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Is Hydrogen Cyanide a Marker of Burkholderia cepacia Complex?
- 1.0422039 - ÚFCH JH 2014 RIV US eng J - Journal Article
Gilchrist, F. J. - Sims, H. - Alcock, A. - Jones, A.M. - Bright-Thomas, R. J. - Smith, D. - Španěl, Patrik - Webb, A. K. - Lenney, W.
Is Hydrogen Cyanide a Marker of Burkholderia cepacia Complex?
Journal of Clinical Microbiology. Roč. 51, č. 11 (2013), s. 3849-3851. ISSN 0095-1137. E-ISSN 1098-660X
Institutional support: RVO:61388955
Keywords : acetone * alcohol * hydrogen cyanide
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 4.232, year: 2013
Biofilm cultures of Burkholderia cepacia complex (BCC) infection have been found to generate the nonvolatile cyanide ion. We investigated if gaseous hydrogen cyanide (HCN) was a marker of BCC infection. Selected ion flow tube mass spectrometry analysis showed HCN was not elevated in the headspace of planktonic or biofilm cultures or in the exhaled breath of adult cystic fibrosis patients with chronic BCC infection. HCN is therefore not an in vitro or in vivo marker of BCC.
Permanent Link: http://hdl.handle.net/11104/0228327
Number of the records: 1