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Overcoming immunoescape mechanisms and induction of CD8(+) T cell-mediated resistance to tumor by polymer-bound doxorubicin conjugate targeted to tumor-specific antigen

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    0390550 - MBÚ 2013 GB eng A - Abstract
    Kovář, Marek - Tomala, Jakub - Etrych, Tomáš - Ulbrich, Karel - Šírová, Milada - Říhová, Blanka
    Overcoming immunoescape mechanisms and induction of CD8(+) T cell-mediated resistance to tumor by polymer-bound doxorubicin conjugate targeted to tumor-specific antigen.
    Immunology 137. Glasgow: Blackwell Publishing Ltd, 2012. Roč. 137, č. 1 (2012), s. 719-719. ISSN 0019-2805. E-ISSN 1365-2567.
    [European Congress of Immunology – ECI 2012. 05.09.2012-08.09.2012, Glasgow]
    R&D Projects: GA ČR GAP301/11/0325; GA ČR GAP301/12/1254
    Institutional support: RVO:61388971 ; RVO:61389013
    Keywords : doxorubicin * HPMA copolymer * tumor
    Subject RIV: EC - Immunology

    This study was focused on interactions of immune system of the host with the tumor during and after the treatment course with doxorubicin bound to HPMA copolymer carrier and targeted with mAb to tumor-specific antigen
    Permanent Link: http://hdl.handle.net/11104/0219427

     
     
Number of the records: 1  

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