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Xenobiotic fluoxetine interacts with the metabolism of thyroid hormones
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SYSNO ASEP 0389387 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Xenobiotic fluoxetine interacts with the metabolism of thyroid hormones Author(s) Pavelka, Stanislav (FGU-C) RID
Tribulová, N. (SK)
Soukup, Tomáš (FGU-C) RIDSource Title Zborník prednášok – z vedeckého sympózia - Priemyselná toxikológia 2012. - Bratislava : Slovenská technická univerzita, 2012 - ISBN 978-80-227-3722-7 Pages s. 139-143 Number of pages 5 s. Publication form Print - P Action Priemyselná toxikológia 2012 /32./ Event date 20.06.2012-22.06.2012 VEvent location Svit, Vysoké Tatry Country SK - Slovakia Event type EUR Language eng - English Country SK - Slovakia Keywords antidepressant drug ; fluoxetine ; iodothyronine deiodinase ; thyroid hormone Subject RIV ED - Physiology R&D Projects GA304/08/0256 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) Annotation With the use of our newly elaborated and adapted radiometric enzyme assays for iodothyronine deiodinases and uridine 5‘-diphospho-glucuronyltransferase, we were able to quantify the effects of subchronic administration of xenobiotic fluoxetine, alone or in combination with 3,5,3’-triiodothyronine, on the metabolism of thyroid hormones in the rats Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2013
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