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Acrosin inhibitor detection along epididymis
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SYSNO ASEP 0388725 Document Type A - Abstract R&D Document Type The record was not marked in the RIV R&D Document Type Není vybrán druh dokumentu Title Acrosin inhibitor detection along epididymis Author(s) Davidová, Nina (BTO-N)
Dorosh, Andriy (BTO-N) RID
Jonáková, Věra (BTO-N) RID
Postlerová, Pavla (BTO-N) ORCID, RIDNumber of authors 4 Source Title Book of abstract. - Praha : Biotechnologický ústav v. v. i. AVČR, 2010 / Pěknicová Jana
S. 67-67Number of pages 1 s. Publication form Print - P Action XVI. symposium českých reprodukčních imunologů s mezinárodní účastí Event date 28.05.2010-30.05.2010 VEvent location Žďár nad Sázavou Country CZ - Czech Republic Event type WRD Language eng - English Country CZ - Czech Republic Keywords Acrosin inhibitor ; Epididymis ; Substrate zymography Subject RIV CE - Biochemistry R&D Projects 1M06011 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA303/09/1285 GA ČR - Czech Science Foundation (CSF) GA523/08/H064 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50520701 - BTO-N (2007-2013) Annotation We registered the increasing signal of acrosin inhibitor (AI) from caput to cauda epididymis. Gene expression of AI increased gradually throughout the epididymal duct, from its entry to the tail. Using specific antibody, AI was localized in the secretory tissues of caput, corpus and cauda epididymis by immunofluorescence. Proteinases and their inhibitors in reproductive fluids may play a significant role in reproduction processes. AI in the reproductive tract inactivates prematurely released sperm acrosin and protects spermatozoa and reproductive epithelium against proteolytic degradation. Workplace Institute of Biotechnology Contact Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Year of Publishing 2013
Number of the records: 1