0386610 - ÚPT 2013 RIV US eng C - Conference Paper (international conference)
Halámek, Josef - Couderc, J. P. - Jurák, Pavel - Vondra, Vlastimil - Leinveber, Pavel - Lipoldová, J. - Novák, M.
Step Responses of Electrical and Mechanical Heart Activity.
Engineering in Medicine and Biology Society (EMBC), 2012 34th Annual International Conference of the IEEE. Piscataway: IEEE, 2012, s. 621. ISBN 978-1-4244-4119-8.
[EMBC 2012. Annual International Conference of the IEEE Engineering in Medicine and Biology Society /34./. San Diego (US), 28.08.2012-01.09.2012]
R&D Projects: GA MŠMT ME09050; GA ČR GAP102/12/2034
Institutional support: RVO:68081731
Keywords : electrical and mechanical heart activity * blood pressure signals
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

Step responses of electrical and blood pressure signals were measured in 19 patients with a BIOTRONIK pacemaker implanted as a response to sudden change of heart rate. The main aim of the study was to look for similarities between the shape of the QT and blood pressure signals tran¬sient responses. The time evolutions of QT intervals, systolic and dia¬stolic blood pressure, pulse pressure and maximal derivative of blood pressure were measured. Averaged results synchronized with heart rate change for steps UP (45 steps) and DOWN (55 steps) are presented. Only fast changes or sharp spikes, generally of a duration of only one beat, exist on transient responses of blood pressure signals. Such changes may be explained by changes in heart filling. The QT step re¬sponse has a well-known shape given by two parts - the immediate change and the slow adaptation. The immediate change of QT intervals may have the same origin as fast changes of blood pressure signals, and may also depend on heart filling, but this hypothesis requires confirmation or rejection by measurements on an isolated heart. The slow adaptation that exists in QT reaction does not exist in blood pressure signals.
Permanent Link: http://hdl.handle.net/11104/0219763