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The expression of NR2B subunit of NMDA receptor in the suprachiasmatic nucleus of Wistar rats and its role in glutamate-induced CREB and ERK1/2 phosphorylation
- 1.0377963 - FGÚ 2013 RIV GB eng J - Journal Article
Bendová, Zdeňka - Sládek, Martin - Svobodová, Irena
The expression of NR2B subunit of NMDA receptor in the suprachiasmatic nucleus of Wistar rats and its role in glutamate-induced CREB and ERK1/2 phosphorylation.
Neurochemistry International. Roč. 61, č. 1 (2012), s. 43-47. ISSN 0197-0186. E-ISSN 1872-9754
R&D Projects: GA ČR GAP303/10/1227
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : circadian clock * NMDA receptor * NR2B subunit * rat * suprachiasmatic nucleus
Subject RIV: FH - Neurology
Impact factor: 2.659, year: 2012
The light entrains circadian clock in the suprachiasmatic nucleus by glutamate receptor mediated activation of ERK and CREB. We show the circadian expression of NMDA glutamate receptor subunit 2B and demonstrate ifenprodil inhibition of glutamate-induced phosporylation of ERK1/2 and CREB in the SCN of rats
Permanent Link: http://hdl.handle.net/11104/0209968
Number of the records: 1