Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?

0570645 - ÚIACH 2024 RIV NL eng J - Journal Article
Týčová, Anna - Přikryl, Jan - Hemzal, D.
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?
TrAC-Trends in Analytical Chemistry. Roč. 161, APR (2023), č. článku 117017. ISSN 0165-9936. E-ISSN 1879-3142
R&D Projects: GA ČR(CZ) GJ20-14069Y
Institutional support: RVO:68081715
Keywords : coupling * electrophoresis * surface-enhanced Raman spectroscopy
OECD category: Analytical chemistry
Impact factor: 13.1, year: 2022
Method of publishing: Limited access

In the past, many detection principles have been developed to trace narrow zones separated via capillary electrophoresis (CE) with various sensitivity and selectivity. While some of them have become mature technologies that are routinely used coupled online with CE, other ones will require further intensive investigation. This is the case of Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) which operate with inelastically scattered photons. The enormously rich chemical and structural information encoded in Raman spectra continuously attracts the attention of researchers striving to develop a robust and reliable coupling of CE and Raman/SERS. In this paper, we provide a systematic overview of the achievements attained in this field with a special focus on the practical aspects that present challenges to CE-Raman/SERS coupling. We also discuss possible future development in this field.
Permanent Link: https://hdl.handle.net/11104/0341964