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Non-cell autonomous and spatiotemporal signalling from a tissue organizer orchestrates root vascular development
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SYSNO ASEP 0553392 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Non-cell autonomous and spatiotemporal signalling from a tissue organizer orchestrates root vascular development Author(s) Yang, B. J. (BE)
Minne, M. (BE)
Brunoni, Federica (UEB-Q) ORCID
Plačková, Lenka (UEB-Q) ORCID, RID
Petřík, Ivan (UEB-Q) ORCID
Sun, Y. (DE)
Nolf, J. (BE)
Smet, W. (BE)
Verstaen, K. (BE)
Wendrich, J.R. (NL)
Eekhout, T. (BE)
Hoyerová, Klára (UEB-Q) RID, ORCID
Van Isterdael, G. (BE)
Haustraete, J. (BE)
Bishopp, A. (GB)
Farcot, E. (GB)
Novák, Ondřej (UEB-Q) RID, ORCID, SAI
Saeys, Y. (BE)
De Rybel, B. (NL)Number of authors 19 Source Title Nature Plants - ISSN 2055-026X
Roč. 7, č. 11 (2021), s. 1485-1494Number of pages 10 s. Language eng - English Country GB - United Kingdom Keywords ARABIDOPSIS ROOT ; BETA-GLUCOSIDASE ; CYTOKININ ACTION OECD category Biochemistry and molecular biology R&D Projects EF16_019/0000827 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support UEB-Q - RVO:61389030 UT WOS 000718877300013 EID SCOPUS 85119157671 DOI 10.1038/s41477-021-01017-6 Annotation During plant development, a precise balance of cytokinin is crucial for correct growth and patterning, but it remains unclear how this is achieved across different cell types and in the context of a growing organ. Here we show that in the root apical meristem, the TMO5/LHW complex increases active cytokinin levels via two cooperatively acting enzymes. By profiling the transcriptomic changes of increased cytokinin at single-cell level, we further show that this effect is counteracted by a tissue-specific increase in CYTOKININ OXIDASE 3 expression via direct activation of the mobile transcription factor SHORTROOT. In summary, we show that within the root meristem, xylem cells act as a local organizer of vascular development by non-autonomously regulating cytokinin levels in neighbouring procambium cells via sequential induction and repression modules. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2022 Electronic address http://doi.org/10.1038/s41477-021-01017-6
Number of the records: 1