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Sex differences in a neurodevelopmental animal model of schizophrenia: focus on white matter structures and myelin
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SYSNO ASEP 0543012 Document Type A - Abstract R&D Document Type The record was not marked in the RIV R&D Document Type Není vybrán druh dokumentu Title Sex differences in a neurodevelopmental animal model of schizophrenia: focus on white matter structures and myelin Author(s) Štark, T. (CZ)
Dražanová, Eva (UPT-D) RID, ORCID, SAI
Vaškovicová, Naděžda (UPT-D) RID, ORCID, SAI
Pekařík, V. (CZ)
Rudá-Kučerová, J. (CZ)
Skoupý, Radim (UPT-D) RID, ORCID, SAI
Kulich, P. (CZ)
Buchtová, Marcela (UZFG-Y) RID, ORCID
Starčuk jr., Zenon (UPT-D) RID, ORCID, SAI
Drago, F. (IT)
Šulcová, A. (CZ)
Micale, V. (IT)Number of authors 12 Source Title European Neuropsychopharmacology. - : Elsevier - ISSN 0924-977X
Roč. 27, Supplement 4 (2017), S890-S891Number of pages 2 s. Publication form Print - P Action Congress of the European-College-of-Neuropsychopharmacology (ECNP) /30./ Event date 02.09.2017 - 05.09.2017 VEvent location Paris Country FR - France Event type WRD Language eng - English Country NL - Netherlands Keywords schizophrenia animal model ; white matter ; myelin ; sex differences Subject RIV BH - Optics, Masers, Lasers OECD category 1.7 Other natural sciences Subject RIV - cooperation Institute of Animal Physiology and Genetics - Genetics ; Molecular Biology Institutional support UPT-D - RVO:68081731 ; UZFG-Y - RVO:67985904 UT WOS 000413847703075 DOI 10.1016/S0924-977X(17)31590-0 Annotation Several clinical studies identify sex differences in the development and clinical expression of schizophrenia (SCZ), with higher incidence and early onset in men. Although white matter dysfunction and myelin impairment seem to play important role in pathophysiology of SCZ, the potential sex differences in this regard have to be elucidated. It is accepted that SCZ may originate from abnormal brain development that only becomes evident in adulthood, thus we assessed if the behavioral changes mimicking SCZ phenotype in both sexes are paralleled with alterations in white matter structures and myelin in a neurodevelopmental animal model of SCZ. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2022
Number of the records: 1