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Stability testing of resveratrol and viniferin obtained from Vitis vinifera L. by various extraction methods considering the industrial viewpoint.
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SYSNO ASEP 0523584 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Stability testing of resveratrol and viniferin obtained from Vitis vinifera L. by various extraction methods considering the industrial viewpoint. Author(s) Kosović, Ema (UCHP-M) SAI
Topiař, Martin (UCHP-M) RID, ORCID, SAI
Cuřínová, Petra (UCHP-M) RID, SAI, ORCID
Sajfrtová, Marie (UCHP-M) RID, ORCID, SAIArticle number 5564 Source Title Scientific Reports. - : Nature Publishing Group - ISSN 2045-2322
Roč. 10, č. 1 (2020)Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords epsilon-viniferin ; monomer resveratrol ; chemistry Subject RIV CI - Industrial Chemistry, Chemical Engineering OECD category Chemical engineering (plants, products) R&D Projects TJ01000249 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) Method of publishing Open access Institutional support UCHP-M - RVO:67985858 UT WOS 000560406800012 EID SCOPUS 85082510999 DOI 10.1038/s41598-020-62603-w Annotation Solid by-products generated in the winemaking process, can comprise valuable bioactive substances such as resveratrol and viniferin, which can be used in whole range of sectors including medicine, pharmacy, cosmetic industry etc. The changes in content of those stilbenes in extracts obtained by maceration and Soxhlet extraction were monitored using newly modified and validated high-performance liquid chromatography-mass spectrometry method which was proved to be accurate, reproducible, and efficient for their determination. The yields of individual bioactive compounds isolated from winery by-products are crucially dependent on the conditions of used extraction techniques. From this point of view, stability testing including light exposure, elevated temperature, and storage for longer time periods in the solution, represents the basis for optimizing conditions of extraction methods of resveratrol and trans-ε-viniferin. High temperature is beneficial for better release of thermally more stable stilbenes such as trans-resveratrol and trans-ε-viniferin but its application for prolonged time periods can be destructive. Light stress conditions cause the formation of otherwise unavailable cis-ε-viniferin by dimerization and photoisomerization of trans- stilbenes. Workplace Institute of Chemical Process Fundamentals Contact Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Year of Publishing 2021 Electronic address https://www.nature.com/articles/s41598-020-62603-w
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