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Ambient Particulate Air Pollution and Daily Mortality in 652 Cities
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SYSNO ASEP 0508320 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Ambient Particulate Air Pollution and Daily Mortality in 652 Cities Author(s) Liu, C. (CN)
Chen, R. (CN)
Sera, F. (GB)
Vicedo-Cabrera, A.M. (GB)
Guo, Y. (CN)
Tong, S. (CN)
Coelho, M. S. Z. S. (BR)
Saldiva, P. H. N. (BR)
Lavigne, E. (CA)
Matus, P. (CL)
Ortega, N. V. (CL)
Garcia, S.O. (CO)
Pascal, M. (FR)
Stafoggia, M. (IT)
Scortichini, M. (IT)
Hashizume, M. (JP)
Honda, Y. (JP)
Hurtado-Diaz, M. (MX)
Cruz, J. (MX)
Nunes, B. (PT)
Teixeira, J. P. (PT)
Kim, H. (KR)
Tobias, A. (ES)
Iniguez, C. (ES)
Forsberg, B. (SE)
Åström, C. (SE)
Ragettli, M.S. (CH)
Guo, Y.L. (TW)
Chen, B. Y. (TW)
Bell, M.L. (US)
Wright, C.Y. (ZA)
Scovronick, N. (US)
Garland, R.M. (ZA)
Milojevic, A. (GB)
Kyselý, Jan (UFA-U) RID, ORCID
Urban, Aleš (UFA-U) RID, ORCID
Orru, H. (EE)
Indermitte, E. (EE)
Jaakkola, J.J.K. (FI)
Ryti, N.R.I. (FI)
Katsouyanni, K. (GR)
Analitis, A. (GR)
Zanobetti, A. (US)
Schwartz, J. (US)
Chen, J. (CN)
Wu, T. (CN)
Cohen, A. (US)
Gasparrini, A. (GB)
Kan, H. (CN)Number of authors 49 Source Title New England Journal of Medicine. - : Massachusetts Medical Society - ISSN 0028-4793
Roč. 381, č. 8 (2019), s. 705-715Number of pages 11 s. Publication form Print - P Language eng - English Country US - United States Keywords time-series ; United States ; health ; association ; multicity ; matter ; metaanalysis ; exposure ; PM2,5 Subject RIV DN - Health Impact of the Environment Quality OECD category Climatic research R&D Projects GA18-22125S GA ČR - Czech Science Foundation (CSF) Method of publishing Limited access Institutional support UFA-U - RVO:68378289 UT WOS 000483203400006 EID SCOPUS 85071318200 DOI 10.1056/NEJMoa1817364 Annotation BackgroundThe systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias.
MethodsWe evaluated the associations of inhalable particulate matter (PM) with an aerodynamic diameter of 10 mu m or less (PM10) and fine PM with an aerodynamic diameter of 2.5 mu m or less (PM2.5) with daily all-cause, cardiovascular, and respiratory mortality across multiple countries or regions. Daily data on mortality and air pollution were collected from 652 cities in 24 countries or regions. We used overdispersed generalized additive models with random-effects meta-analysis to investigate the associations. Two-pollutant models were fitted to test the robustness of the associations. Concentration-response curves from each city were pooled to allow global estimates to be derived.
ResultsOn average, an increase of 10 mu g per cubic meter in the 2-day moving average of PM10 concentration, which represents the average over the current and previous day, was associated with increases of 0.44% (95% confidence interval [CI], 0.39 to 0.50) in daily all-cause mortality, 0.36% (95% CI, 0.30 to 0.43) in daily cardiovascular mortality, and 0.47% (95% CI, 0.35 to 0.58) in daily respiratory mortality. The corresponding increases in daily mortality for the same change in PM2.5 concentration were 0.68% (95% CI, 0.59 to 0.77), 0.55% (95% CI, 0.45 to 0.66), and 0.74% (95% CI, 0.53 to 0.95). These associations remained significant after adjustment for gaseous pollutants. Associations were stronger in locations with lower annual mean PM concentrations and higher annual mean temperatures. The pooled concentration-response curves showed a consistent increase in daily mortality with increasing PM concentration, with steeper slopes at lower PM concentrations.
ConclusionsOur data show independent associations between short-term exposure to PM10 and PM2.5 and daily all-cause, cardiovascular, and respiratory mortality in more than 600 cities across the globe. These data reinforce the evidence of a link between mortality and PM concentration established in regional and local studies. (Funded by the National Natural Science Foundation of China and others.)
Modeling of the associations between mortality and air pollution data from 652 cities, mostly in the northern hemisphere, showed that concentrations of inhalable and fine particulate matter were associated with daily all-cause, cardiovascular, and respiratory mortality. An interactive map allows the reader to explore the geographic distribution of PM, and a Quick Take summarizes the findings in a short video.Workplace Institute of Atmospheric Physics Contact Kateřina Adamovičová, adamovicova@ufa.cas.cz, Tel.: 272 016 012 ; Kateřina Potužníková, kaca@ufa.cas.cz, Tel.: 272 016 019 Year of Publishing 2020 Electronic address https://www.nejm.org/doi/pdf/10.1056/NEJMoa1817364?articleTools=true
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