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Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat

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    0507518 - ÚMG 2020 RIV GB eng J - Journal Article
    Šeda, Ondřej - Křenová, D. - Oliyarnyk, O. - Šedová, Lucie - Krupková, M. - Liška, F. - Chylíková, B. - Kazdová, L. - Křen, V.
    Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat.
    Lipids in Health and Disease. Roč. 15, November (2016), č. článku 199. E-ISSN 1476-511X
    Institutional support: RVO:68378050
    Keywords : Connexin * Animal models * Lipoprotein * Oxidative stress * Metabolic syndrome
    OECD category: Cell biology
    Impact factor: 2.073, year: 2016
    Method of publishing: Open access
    https://lipidworld.biomedcentral.com/articles/10.1186/s12944-016-0376-3

    Background: Several members of connexin family of transmembrane proteins were previously implicated in distinct metabolic conditions. In this study we aimed to determine the effects of complete and heterozygous form of connexin50 gene (Gja8) mutation L7Q on metabolic profile and oxidative stress parameters in spontaneously hypertensive inbred rat strain (SHR).
    Permanent Link: http://hdl.handle.net/11104/0298508

     
     
Number of the records: 1  

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