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Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver

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    SYSNO ASEP0443146
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleMelatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver
    Author(s) Houdek, Pavel (FGU-C) ORCID
    Polidarová, Lenka (FGU-C) RID, ORCID
    Nováková, Marta (FGU-C)
    Matějů, Kristýna (FGU-C)
    Kubík, Štěpán (FGU-C) RID, ORCID
    Sumová, Alena (FGU-C) RID, ORCID
    Source TitleDevelopmental Neurobiology - ISSN 1932-8451
    Roč. 75, č. 2 (2015), s. 131-144
    Number of pages21 s.
    Languageeng - English
    CountryUS - United States
    Keywordsontogenesis ; circadian system ; suprachiasmatic nuclei ; clock gene ; melatonin
    Subject RIVFH - Neurology
    R&D ProjectsGAP303/12/1108 GA ČR - Czech Science Foundation (CSF)
    Institutional supportFGU-C - RVO:67985823
    UT WOS000347798900002
    EID SCOPUS84920850250
    DOI10.1002/dneu.22213
    AnnotationThe aim of the study was to ascertain the role of maternal melatonin in entrainment of the fetal circadian clocks. The role of maternal melatonin in the entrainment of fetal circadian clocks has been suggested, but direct evidence was lacking. The data demonstrate that in pregnant rats with suppressed endogenous melatonin levels, application of melatonin affects the fetal clock in the SCN but not in the liver
    WorkplaceInstitute of Physiology
    ContactLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Year of Publishing2016
Number of the records: 1  

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