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Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver
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SYSNO ASEP 0443146 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver Author(s) Houdek, Pavel (FGU-C) ORCID
Polidarová, Lenka (FGU-C) RID, ORCID
Nováková, Marta (FGU-C)
Matějů, Kristýna (FGU-C)
Kubík, Štěpán (FGU-C) RID, ORCID
Sumová, Alena (FGU-C) RID, ORCIDSource Title Developmental Neurobiology - ISSN 1932-8451
Roč. 75, č. 2 (2015), s. 131-144Number of pages 21 s. Language eng - English Country US - United States Keywords ontogenesis ; circadian system ; suprachiasmatic nuclei ; clock gene ; melatonin Subject RIV FH - Neurology R&D Projects GAP303/12/1108 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 UT WOS 000347798900002 EID SCOPUS 84920850250 DOI 10.1002/dneu.22213 Annotation The aim of the study was to ascertain the role of maternal melatonin in entrainment of the fetal circadian clocks. The role of maternal melatonin in the entrainment of fetal circadian clocks has been suggested, but direct evidence was lacking. The data demonstrate that in pregnant rats with suppressed endogenous melatonin levels, application of melatonin affects the fetal clock in the SCN but not in the liver Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2016
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