Gold Nanoparticles for High Resolution Imaging in Modern Immunocytochemistry

0440603 - BFÚ 2015 RIV NL eng J - Journal Article
Schroefel, A. - Cmarko, D. - Bártová, Eva - Raška, I.
Gold Nanoparticles for High Resolution Imaging in Modern Immunocytochemistry.
INTRACELLULAR DELIVERY II: FUNDAMENTALS AND APPLICATIONS. Roč. 7, č. 2014 (2014), s. 189-206. ISSN 1559-7083
Institutional support: RVO:68081707
Keywords : CRYO-ELECTRON-MICROSCOPY * CELLULAR UPTAKE * IMMUNOELECTRON MICROSCOPY
Subject RIV: BO - Biophysics

This perspective presents the possibilities for utilization of gold nanoparticles in immunocytochemistry. The unique combination of gold nanoparticle properties is just beginning to be fully recognized for the range of diagnostic and therapeutic applications. The current findings from bionanotechnology and emerging cryo-electron microscopy techniques can lead to novel perspectives for targeted delivery of gold conjugates into cells and tissues. The chapter offers a survey of modern electron microscopy methods with a special focus on immunolabeling. We also discuss the impact of gold nanoparticles on cellular systems and the potential possibilities for their targeted delivery into cells and tissues.
Permanent Link: http://hdl.handle.net/11104/0243728