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In vitro T lymphocyte adherence capabilities under the influence of lower induction values (0.1-0.01 mT) of 50 Hz external magnetic fields
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SYSNO ASEP 0436558 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title In vitro T lymphocyte adherence capabilities under the influence of lower induction values (0.1-0.01 mT) of 50 Hz external magnetic fields Author(s) Čoček, A. (CZ)
Jandová, Anna (URE-Y)
Hahn, A. (CZ)
Mártonová, J. (CZ)
Ambruš, M. (CZ)
Dohnalová, A. (CZ)
Nedbalová, M. (CZ)
Pokorný, Jiří (URE-Y) RIDNumber of authors 8 Source Title 9TH INTERNATIONAL FROHLICH'S SYMPOSIUM: ELECTRODYNAMIC ACTIVITY OF LIVING CELLS (INCLUDING MICROTUBULE COHERENT MODES AND CANCER CELL PHYSICS), 329. - Bristol : IOP, 2011 / Cifra Michal ; Pokorny Jiří ; Kučera Ondřej - ISSN 1742-6588 Pages 012031 Number of pages 10 s. Publication form Print - P Action 9th International Frohlich's Symposium on Electrodynamic Activity of Living Cells - Including Microtubule Coherent Modes and Cancer Cell Physics Event date 01.07.2011-03.07.2011 VEvent location Praha Country CZ - Czech Republic Event type WRD Language eng - English Country GB - United Kingdom Keywords Cancer patients ; Control groups ; External magnetic field Subject RIV JA - Electronics ; Optoelectronics, Electrical Engineering CEZ AV0Z20670512 - URE-Y (2005-2011) UT WOS 000300166500031 EID SCOPUS 84859534176 DOI 10.1088/1742-6596/329/1/012031 Annotation Our research thus far has concerned the impact of external magnetic fields (50 Hz) and low (0.01-10 mT) induction on adherence capabilities of T lymphocytes obtained from the blood of patients with head and neck tumors. We know that the in vitro adherence capability of T lymphocytes towards surfaces in cancer patients is less than that of control. Previously, we have found that exposure to magnetic fields (50 Hz / 0.01-10 mT) increases the capability of T lymphocytes, in larynx/pharynx cancer patients, to adhere in vitro to surfaces, achieving almost physiological values, in not only pre-treatment patients but also those receiving treatment in the course of follow-up. The capability of T lymphocytes in controls (voluntary blood donors) to adhere to surfaces was also increased (50 Hz / 0.01-0.5 mT). The present study concentrates on the significance of the level of magnetic field induction in order to determine whether low induction values can restore T lymphocytes adherence capabilities. Testing a set of 20 patients showed a statistically significant difference (p < 0.05) in the in vitro adherence capacity of T lymphocytes between both 0.01 and 0.05, and 0.1 mT induction levels. In the control group (patients diagnosed with chronic sensorineural hearing loss) there was even a statistically significant difference between induction values of 0.05 and 0.01 mT. Therefore, we concluded that lower induction values resulted in a more biologically significant response Workplace Institute of Radio Engineering and Electronics Contact Petr Vacek, vacek@ufe.cz, Tel.: 266 773 413, 266 773 438, 266 773 488 Year of Publishing 2015
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