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Expression of 11 beta-hydroxysteroid dehydrogenase type 2 is deregulated in colon carcinoma
- 1.0428060 - FGÚ 2015 RIV ES eng J - Journal Article
Moravec, Martin - Švec, Jiří - Ergang, Peter - Mandys, V. - Řeháková, Lenka - Zádorová, Z. - Hajer, J. - Kment, M. - Pácha, Jiří
Expression of 11 beta-hydroxysteroid dehydrogenase type 2 is deregulated in colon carcinoma.
Histology and Histopathology. Roč. 29, č. 4 (2014), s. 489-496. ISSN 0213-3911. E-ISSN 1699-5848
R&D Projects: GA MZd(CZ) NS9982; GA ČR(CZ) GA13-08304S
Grant - others:Univerzita Karlova(CZ) 70310; Univerzita Karlova(CZ) Prvouk P27; Univerzita Karlova(CZ) CZ.2.16/3.1.00/24024
Institutional support: RVO:67985823
Keywords : 11beta-hydroxysteroid dehydrogenase * colorectal polyp * adenoma
Subject RIV: ED - Physiology
Impact factor: 2.096, year: 2014
The results demonstrate that the downregulation of 11HSD2, an enzyme which increases the local concentration of cortisol due to the reduction of cortisone, is a typical feature of the development of colorectal polypous lesions and their transformation into CRC
Permanent Link: http://hdl.handle.net/11104/0233452
Number of the records: 1