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Development of a human mitochondrial oligonucleotide microarray (h-MitoArray) and gene expression analysis of fibroblast cell lines from 13 patients with isolated F1Fo ATP synthase deficiency
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SYSNO ASEP 0318461 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Development of a human mitochondrial oligonucleotide microarray (h-MitoArray) and gene expression analysis of fibroblast cell lines from 13 patients with isolated F1Fo ATP synthase deficiency Title Vývoj lidského mitochondriálního oligonukleotidového čipu (h-MitoArray) Author(s) Čížková, Alena (FGU-C)
Stránecký, V. (CZ)
Ivánek, Robert (UMG-J)
Hartmannová, H. (CZ)
Nosková, L. (CZ)
Piherová, L. (CZ)
Tesařová, M. (CZ)
Hansíková, H. (CZ)
Honzík, T. (CZ)
Zeman, J. (CZ)
Divina, Petr (UMG-J)
Potocká, A. (CZ)
Paul, J. (CZ)
Sperl, W. (AT)
Mayr, J. A. (AT)
Seneca, S. (BE)
Houštěk, J. (CZ)
Kmoch, S. (CZ)Source Title BMC Genomics. - : BioMed Central - ISSN 1471-2164
Roč. 9, - (2008), s. 38-38Number of pages 1 s. Language eng - English Country GB - United Kingdom Keywords microarray ; mitochondria ; F1Fo ATP synthase deficiency Subject RIV EB - Genetics ; Molecular Biology R&D Projects GD303/03/H065 GA ČR - Czech Science Foundation (CSF) GA303/07/0781 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) AV0Z50520514 - UMG-J (2005-2011) UT WOS 000253987500001 DOI 10.1186/1471-2164-9-38 Annotation We have developed and validated an oligonucleotide microarray (h-MitoArray) allowing expression analysis of 1632 human genes playing role in mitochondria biology, cell cycle regulation, signal transduction and apoptosis. Using the h-MitoArray we analyzed gene expression profiles in 9 control and 13 fibroblast cell lines from patients with F1Fo ATP synthase deficiency. Workplace Institute of Molecular Genetics Contact Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Year of Publishing 2009
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