A novel approach to surface plasmon resonance multichannel sensing

0303951 - URE-Y 20020027 RIV US eng C - Conference Paper (international conference)
Homola, Jiří - Dostálek, Jakub - Čtyroký, Jiří
A novel approach to surface plasmon resonance multichannel sensing.
Bellingham: SPIE The International Society for Optical Engineering, 2001. Proceedings of SPIE., 4416. ISSN 0277-786X. In: ICOSN 2001 Optical Engineering for Sensing and Nanotechnology. - (Iwata, K.), s. 86-89
[ICOSN 2001 Optical Engineering for Sensing and Nanotechnology. Yokohama (JP), 06.06.2001-08.06.2001 (K)]
R&D Projects: GA ČR GA102/99/0549; GA ČR GA102/00/1536
Institutional research plan: CEZ:AV0Z2067918
Keywords : surface plasmon resonance * sensors * biosensors
Subject RIV: JB - Sensors, Measurment, Regulation

We present a novel surface plasmon resonance (SPR) sensor based on serial organization of sensing channels and sequential spectral encoding of responses from sensing channels into an optical spectrum. This approach allows probing interfacial processes by surface plasmons of different field profiles which makes it possible to distinguish surface and bulk contributions to SPR sensor response. We illustrate this unique feature of the presented approach in a model biosensing experiment in which the detection of human chorigonadotropin (hCG) is compensated for background refractive index interference.
Permanent Link: http://hdl.handle.net/11104/0114095