Binding of D-mannose to poly(2-hydroxyethyl methacrylate) hydrogels by azo coupling

0189109 - UMCH-V 20033063 RIV NL eng J - Journal Article
Labský, Jiří
Binding of D-mannose to poly(2-hydroxyethyl methacrylate) hydrogels by azo coupling.
Biomaterials. Roč. 24, č. 22 (2003), s. 4031-4036. ISSN 0142-9612. E-ISSN 1878-5905
R&D Projects: GA ČR GA203/00/1310
Institutional research plan: CEZ:AV0Z4050913
Keywords : mannose * hydrogels * mannose-rich hydrogels
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.903, year: 2003

Crosslinked hydrogels based on poly(2-hydroxyethyl methacrylate) poly(HEMA) were prepared and modified with tyramine [4-(2-aminoethyl)phenol] to enable azo coupling with mannosyl derivatives; copolymerization of HEMA with polymerizable activated esters and surface modification reaction with 4-nitrophenyl chlorocarbonate for activation of the hydrogels were used.
Permanent Link: http://hdl.handle.net/11104/0002622