Nuclear DNA helicase II is recruited to IFN-alfa-activated transcription sites at PML nuclear bodies
1.
SYSNO ASEP
0173581
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Nuclear DNA helicase II is recruited to IFN-alfa-activated transcription sites at PML nuclear bodies
Author(s)
Fuchsová, Beáta (UEM-P) Novák, P. (CZ) Kafková, J. (CZ) Hozák, Pavel (UEM-P)
Source Title
Journal of Cell Biology. - : Rockefeller University Press
- ISSN 0021-9525
Roč. 158, č. 3 (2002), s. 463-473
Number of pages
11 s.
Language
eng - English
Country
US - United States
Keywords
nuclear DNA helicase II ; RNA helicase A ; PML nuclear body
Subject RIV
EB - Genetics ; Molecular Biology
R&D Projects
IAA5039701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ
AV0Z5039906 - UEM-P
MSM 111310001
Annotation
We report for the first time that some NDH II/RNA helicase A is a component of promyelocytic leukemia nuclear bodies (PML NBs). We suggest that DNH II recruitment to PML NBs is connected with transcriptional regulation of interferon-α-inducible genes attached to PML NBs.
