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Capillary electrophoretic separation of enantiomers of nucleotide-based antiviral drugs using beta-cyclodextrin as chiral selector

  1. 1.
    SYSNO ASEP0099766
    Document TypeC - Proceedings Paper (int. conf.)
    R&D Document TypeConference Paper
    TitleCapillary electrophoretic separation of enantiomers of nucleotide-based antiviral drugs using beta-cyclodextrin as chiral selector
    TitleKapilárně elektroforetická separace enantiomerů nukleotidových antivirových léčiv s využitím beta-cyklodextrinu jako chirálního selektor
    Author(s) Šolínová, Veronika (UOCHB-X) RID, ORCID
    Kašička, Václav (UOCHB-X) RID, ORCID
    Holý, Antonín (UOCHB-X)
    Source Title13th International Symposium on Separation Sciences. - - : -, 2007 - ISBN 978-80-227-2698-6
    Pagesp02
    Number of pages3 s.
    ActionInternational Symposium on Separation Sciences /13./
    Event date27.06.2007-29.06.2007
    VEvent locationŠtrbské Pleso
    CountrySK - Slovakia
    Event typeWRD
    Languageeng - English
    CountrySK - Slovakia
    Keywordscapillary affinity electrophoresis ; antiviral drugs ; enantiomer separation
    Subject RIVCB - Analytical Chemistry, Separation
    R&D ProjectsGA203/05/2539 GA ČR - Czech Science Foundation (CSF)
    GA203/06/1044 GA ČR - Czech Science Foundation (CSF)
    1QS400550501 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    1M0508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z40550506 - UOCHB-X (2005-2011)
    AnnotationR,S-enantiomers of important acyclic nucleoside phosphonate-based antiviral drugs (9-[2-(phosphonomethoxy)-propyl] adenine, PMPA, and 9-[2-hydroxy-3-(phosphonomethoxy)propyl]adenine, HPMPA) were separated by capillary electrophoresis in borate background electrolyte using beta-cyclodextrin as chiral selector.
    WorkplaceInstitute of Organic Chemistry and Biochemistry
    Contactasep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
    Year of Publishing2008
Number of the records: 1  

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