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Degradation of mechanical properties of magnesium alloy
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SYSNO ASEP 0534523 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Degradation of mechanical properties of magnesium alloy Author(s) Sedláček, R. (CZ)
Suchý, Tomáš (USMH-B) RID, ORCID, SAI
Padovec, Z. (CZ)Source Title Experimental Stress Analysis (EAN 2019). - Praha : Česká společnost pro mechaniku, 2019 / Petruška J. ; Návrat T. ; Houfek L. ; Šebek F. - ISBN 978-802145766-9 Pages s. 459-461 Number of pages 3 s. Publication form Online - E Action International Scientific Conference on Experimental Stress Analysis /57./ EAN 2019 Event date 03.06.2019 - 06.06.2019 VEvent location Luhačovice Country CZ - Czech Republic Event type WRD Language eng - English Country CZ - Czech Republic Keywords Bioabsorbable metals ; Biodegradation ; Magnesium ; Implant Subject RIV JJ - Other Materials OECD category Applied mechanics Institutional support USMH-B - RVO:67985891 UT WOS 000568113800071 EID SCOPUS 85071226036 Annotation In this study, biodegradation behaviour of WE43 magnesium alloy have been studied and compared during exposure to three different media commonly used to simulate the conditions of human body environment. Magnesium alloys emerged as a new class of bioresorbable implant materials. Their applications reduce certain risks associated with conventional permanent implants. Biodegradation behaviour of the WE43 magnesium alloy was observed under Dulbecco Modified Eagle Medium (DMEM, Sigma Aldrich) supplemented with 5 % fetal bovine serum and gentamicin antibiotic as standard. The samples were stored in the medium at 37 degrees C and in a 5 % CO2 atmosphere. The second type of medium was Hank's Salt Balanced Solution (HBSS, Sigma Aldrich), which simulates the inorganic composition of blood plasma. HBSS was tempered at 37 degrees C. The last solution was an acidic solution of HCl + NaCl (pH2) with pH similar to 2 (0.01M HCl and 0.14M NaCl) tempered at 37 degrees C. The acidic type of solution was used to simulate a local acidic environment associated with osteoclast activity during bone remodelling. Changes in the mechanical properties of the samples during exposure to simulated body conditions were observed. Workplace Institute of Rock Structure and Mechanics Contact Iva Švihálková, svihalkova@irsm.cas.cz, Tel.: 266 009 216 Year of Publishing 2021 Electronic address https://www.researchgate.net/publication/333679700_Degradation_of_mechanical_properties_of_magnesium_alloy
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