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Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use
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SYSNO ASEP 0532862 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use Author(s) Hocek, Michal (UOCHB-X) RID, ORCID
Tokarenko, Anna (UOCHB-X)
Smolen, Sabina (UOCHB-X)
Hajdúch, M. (CZ)
Džubák, P. (CZ)Year of issue 2020 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested A - Poskytovatel licence požaduje licenční poplatek Patent no. or utility model no. or industrial design no. CA3031049 Date of the patent acceptance 07.07.2020 Name of the patent owner Ústav organické chemie a biochemie AV ČR, v. v. i. - Univerzita Palackého v Olomouci Code of the issuer name CA001 - Canadian Intellectual Property Office (CIPO) Gatineau, Québec Current use A - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem Language eng - English Keywords nucleosides ; cytostatics ; deazapurines Subject RIV CC - Organic Chemistry OECD category Medicinal chemistry R&D Projects GA16-00178S GA ČR - Czech Science Foundation (CSF) TE01020028 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) Institutional support UOCHB-X - RVO:61388963 Annotation Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides of general formula (I), where R is selected from the group comprising furan-2-yl, furan-3-yl, benzofuran-2-yl, methylsulfanyl, methoxy, amino, dimethylamino, methyl or chloro, and pharmaceutically acceptable salt thereof, their optical isomers and mixtures of such optical isomers. Compounds according to the invention show strong cytostatic and cytotoxic effects on cell lines in a wide variety of diseases including tumors of various histogenic origin. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2021 Electronic address https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=CA&NR=3031049C&KC=C&FT=D&ND=4&date=20200707&DB=&locale=en_EP
Number of the records: 1