Number of the records: 1
Low-level fat fraction quantification at 3 T: comparative study of different tools for water-fat reconstruction and MR spectroscopy
- 1.
SYSNO ASEP 0522218 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Low-level fat fraction quantification at 3 T: comparative study of different tools for water-fat reconstruction and MR spectroscopy Author(s) Kořínek, Radim (UPT-D) RID, ORCID, SAI
Gajdošík, M. (AT)
Trattnig, S. (AT)
Starčuk jr., Zenon (UPT-D) RID, ORCID, SAI
Krššák, M. (AT)Number of authors 5 Article number - Source Title Magnetic Resonance Materials in Physics, Biology and Medicine. - : Springer - ISSN 0968-5243
-, JAN (2020)Number of pages 14 s. Publication form Online - E Language eng - English Country GB - United Kingdom Keywords low-level fat fraction ; proton density fat fraction ; quantification ; MR imaging ; MR spectroscopy Subject RIV BH - Optics, Masers, Lasers OECD category Radiology, nuclear medicine and medical imaging R&D Projects ED0017/01/01 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LO1212 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 8J18AT023 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support UPT-D - RVO:68081731 UT WOS 000509140200001 DOI 10.1007/s10334-020-00825-9 Annotation Objectives Chemical Shift Encoded Magnetic Resonance Imaging (CSE-MRI)-based quantification of low-level (< 5% of proton density fat fraction-PDFF) fat infiltration requires highly accurate data reconstruction for the assessment of hepatic or pancreatic fat accumulation in diagnostics and biomedical research. Materials and methods We compare three software tools available for water/fat image reconstruction and PDFF quantification with MRS as the reference method. Based on the algorithm exploited in the tested software, the accuracy of fat fraction quantification varies. We evaluate them in phantom and in vivo MRS and MRI measurements. Results The signal model of Intralipid 20% emulsion used for phantoms was established for 3 T and 9.4 T fields. In all cases, we noticed a high coefficient of determination (R-squared) between MRS and MRI-PDFF measurements: in phantoms, and in vivo . Bland-Altman analysis was applied to phantom and in vivo measurements. Discussion Multi-echo MRI in combination with an advanced algorithm including multi-peak spectrum modeling appears as a valuable and accurate method for low-level PDFF quantification over large FOV in high resolution, and is much faster than MRS methods. The graph-cut algorithm (GC) showed the fewest water/fat swaps in the PDFF maps, and hence stands out as the most robust method of those tested. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2020 Electronic address https://link.springer.com/content/pdf/10.1007%2Fs10334-020-00825-9.pdf
Number of the records: 1