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Quantification of structural changes of UHMWPE components in total joint replacements
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SYSNO ASEP 0427703 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Quantification of structural changes of UHMWPE components in total joint replacements Author(s) Fulín, P. (CZ)
Pokorný, D. (CZ)
Šlouf, Miroslav (UMCH-V) RID, ORCID
Nevoralová, Martina (UMCH-V) RID, ORCID
Vacková, Taťana (UMCH-V) RID
Dybal, Jiří (UMCH-V) RID, ORCID
Pilař, Jan (UMCH-V) RID, ORCIDSource Title BMC Musculoskeletal Disorders
Roč. 15, 28 March (2014), 109_1-109_8Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords UHMWPE ; oxidative damage ; residual radicals Subject RIV FI - Traumatology, Orthopedics R&D Projects TA01011406 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) NT12229 GA MZd - Ministry of Health (MZ) Institutional support UMCH-V - RVO:61389013 UT WOS 000335183900002 EID SCOPUS 84898426501 DOI 10.1186/1471-2474-15-109 Annotation At present time the number of implantations of joint replacements as well as their revisions increases. Higher demands are required on the quality and longevity of implants. The aim of this work was to determine the degree of oxidative degradation and the amount of free/residual radicals in selected ultra-high molecular weight polyethylene (UHMWPE) components of the joint replacements and demonstrate that the measured values are closely connected with quality and lifetime of the polymer components. We tested both new (4 samples) and explanted (4 samples) UHMWPE polymers for total joint replacements. The samples were characterized by infrared spectroscopy (IR), electron spin resonance (ESR) and microhardness (MH) test. The IR measurements yielded the values of oxidation index and trans-vinylene index. The ESR measurements gave the free radicals concentration. In the group of new polyethylene components, we found oxidation index values ranging from 0.00-0.03 to 0.24. The trans-vinylene index values ranged from 0.044 to 0.080. The value of free radical concentration was zero in virgin and also in sample of Beznoska Company and non-zero in the other samples. In the group of explanted components, the measured values were associated with their history, micromechanical properties and performance in vivo. We demonstrated that measuring of oxidative damage may help the orthopaedic surgeon in estimating the quality of UHMWPE replacement component and thus radically to avoid early joint replacement failure due to worse polyethylene quality. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2015
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