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HMGB1 interacts with human topoisomerase IIalpha and stimulates its catalytic activity

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    0345271 - BFÚ 2011 RIV GB eng J - Journal Article
    Štros, Michal - Bačíková, Alena - Muselíková Polanská, Eva - Štokrová, Jitka - Strauss, F.
    HMGB1 interacts with human topoisomerase IIalpha and stimulates its catalytic activity.
    Nucleic Acids Research. Roč. 35, č. 15 (2007), s. 5001-5013. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA ČR(CZ) GA204/05/2031; GA AV ČR(CZ) IAA400040702
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z50520514; CEZ:AV0Z50520701
    Keywords : HMGB1 * DNA topoisomerase IIalpha * DNA repair
    Subject RIV: BO - Biophysics
    Impact factor: 6.954, year: 2007

    DNA topoisomerase IIalpha (topo IIalpha) is an essential nuclear enzyme and its unique decatenation activity has been implicated in many aspects of chromosome dynamics such as chromosome replication and segregation during mitosis.
    Permanent Link: http://hdl.handle.net/11104/0186585

     
     
Number of the records: 1  

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