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Activation of pro-survival pathways during non-adherent cultivation causes cell resistance to TRAIL-induced apoptosis

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    0330522 - BFÚ 2010 FR eng A - Abstract
    Kočí, Lenka - Hýžďalová, Martina - Hofmanová, Jiřina - Kozubík, Alois
    Activation of pro-survival pathways during non-adherent cultivation causes cell resistance to TRAIL-induced apoptosis.
    [Aktivace drah podporujících přežití buněk během neadherentní kultivace způsobuje rezistenci buněk k apoptóze indukované TRAIL.]
    Abstract Book. Paris, 2009. s. 246.
    [17th ECDO Euroconference on Apoptosis, Destruction, Degradation and Death Cell Death Control in Cancer and Neurodegeneration, 6th Training Course on Concepts and Methods in Programmed Cell Death. 23.09.2009-26.09.2009, Paris]
    R&D Projects: GA ČR(CZ) GA305/09/1526; GA ČR(CZ) GA524/07/1178; GA AV ČR(CZ) 1QS500040507
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : adhesion * TRAIL * P13K/Akt pathway
    Subject RIV: BO - Biophysics

    The aim of this study was to observe differences in TRAIL-induced apoptosis during non-adherent and adherent cultivation, and investigate the mechanisms involved.

    Cílem studie bylo sledovat rozdíly v apoptóze indukované TRAIL během adherentní a neadherentní kultivace. Zároveň také hledat příslušné mechanizmy zahrnuté v těchto procesech.
    Permanent Link: http://hdl.handle.net/11104/0176296

     
     
Number of the records: 1  

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