Reverse effect of indomethacin on the immunosuppressive activity of boar seminal immunosuppressive fraction
1.
SYSNO ASEP
0191437
Document Type
J - Journal Article
R&D Document Type
Journal Article
Subsidiary J
Ostatní články
Title
Reverse effect of indomethacin on the immunosuppressive activity of boar seminal immunosuppressive fraction
Author(s)
Veselský, Leopold (UMG-J) Dostál, J. (CZ) Kraus, Marek (UMG-J) Pěknicová, Jana (UMG-J) Holáň, Vladimír (UMG-J) Zajícová, Alena (UMG-J) Jonáková, Věra (UMG-J) Železná, Blanka (UMG-J)
GA303/01/0615 GA ČR - Czech Science Foundation (CSF)
NI6883 GA MZd - Ministry of Health (MZ)
CEZ
AV0Z5052915 - UMG-J
Annotation
The inhibitory activity of seminal immunosuppressive fraction (ISF) on mitogen-stimulated lymphocyte proliferation and on production of antibody to a soluble antigen was modified by indomethacin or monoclonal antibody to ISF. ISF contains PSP spermadhesins (glycosylated) and if their immunosuppressive activity is caused by their sacharide or protein part of their molecule.