Number of the records: 1
Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment
- 1.0448675 - ÚEB 2016 RIV FR eng J - Journal Article
Bártíková, H. - Skálová, L. - Stuchlíková, L. - Vokřál, I. - Vaněk, Tomáš - Podlipná, Radka
Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment.
Drug Metabolism Reviews. Roč. 47, č. 3 (2015), s. 374-387. ISSN 0360-2532. E-ISSN 1097-9883
R&D Projects: GA ČR(CZ) GA15-05325S; GA ČR(CZ) GA14-22593S
Institutional support: RVO:61389030
Keywords : Pollutants * phytoremediation * drug phytotoxicity
Subject RIV: CE - Biochemistry
Impact factor: 4.526, year: 2015
http://www.tandfonline.com/doi/abs/10.3109/03602532.2015.1076437
Many various xenobiotics permanently enter plants and represent potential danger for their organism. For that reason, plants have evolved extremely sophisticated detoxification systems including a battery of xenobiotic-metabolizing enzymes. Some of them are similar to those in humans and animals, but there are several plant-specific ones. This review briefly introduces xenobiotic-metabolizing enzymes in plants and summarizes present information about their action toward veterinary drugs. Veterinary drugs are used worldwide to treat diseases and protect animal health. However, veterinary drugs are also unwantedly introduced into environment mostly via animal excrements, they persist in the environment for a long time and may impact on the non-target organisms. Plants are able to uptake, transform the veterinary drugs to non- or less-toxic compounds and store them in the vacuoles and cell walls. This ability may protect not only plant themselves but also other organisms, predominantly invertebrates and wild herbivores. The aim of this review is to emphasize the importance of plants in detoxification of veterinary drugs in the environment. The results of studies, which dealt with transport and biotransformation of veterinary drugs in plants, are summarized and evaluated. In conclusion, the risks and consequences of veterinary drugs in the environment and the possibilities of phytoremediation technologies are considered and future perspectives are outlined.
Permanent Link: http://hdl.handle.net/11104/0250303
File Download Size Commentary Version Access 2015_Bartikova_DRUG METABOLISM REVIEWS_374.pdf 11 418.6 KB Other open-access
Number of the records: 1