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Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives A structure activity relationship study

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    0616886 - ÚEB 2025 RIV FR eng J - Journal Article
    Maková, B. - Mik, V. - Lišková, B. - Drašarová, Lenka - Medvedíková, M. - Hořínková, A. - Vojta, P. - Zatloukal, M. - Plíhalová, L. - Hönig, M. - Doležal, Karel - Forejt, K. - Oždian, T. - Hajdúch, M. - Strnad, Miroslav - Voller, J.
    Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives A structure activity relationship study.
    European Journal of Medicinal Chemistry. Roč. 284, FEB 15 (2025), č. článku 117176. ISSN 0223-5234. E-ISSN 1768-3254
    Institutional support: RVO:61389030
    Keywords : familial dysautonomia * cell-line * ikbkap * gene * protein * inhibition * expression * model * brain * quantification * Kinetin * Cytokinin * elp1 * Alternative splicing * mRNA metabolism * ADME in vitro
    OECD category: Medicinal chemistry
    Impact factor: 6, year: 2023 ; AIS: 0.979, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1016/j.ejmech.2024.117176DOI: https://doi.org/10.1016/j.ejmech.2024.117176
    Permanent Link: https://hdl.handle.net/11104/0363873
     
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    2025_Makova_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_117176.pdf16.8 MBOtheropen-access
     
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