Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje

0567981 - ÚČL 2023 RIV US eng J - Journal Article
Cavero, I. - Holzgrefe, H.
Remembering the canonical discoverers of the core components of the mammalian cardiac conduction system: Keith and Flack, Aschoff and Tawara, His, and Purkinje.
Advances in Physiology Education. Roč. 46, č. 4 (2022), s. 549-579. ISSN 1043-4046. E-ISSN 1522-1229
Research Infrastructure: CLB II - 90136
Keywords : atrioventricular node * intranodal and intraratrial pathways * Purkinje fiber * sinus-atrial node
OECD category: Specific literatures
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://journals.physiology.org/doi/full/10.1152/advan.00072.2022

This report presents the first comprehensive summary of the factors enabling the discovery of the cardiac conduction system (CCS). Biographical highlights and achievements of the CCS canonical discoverers, hypotheses concerning mechanisms underlying sinus node (SAN) automaticity, use of eponyms to denominate a discovery, famous controversies, possible reproachable behavior (e.g., intellectual support for eugenics in post-World War I Germany) by two of the discoverers, and examples of historical mentor-pupil relationships are discussed.
Permanent Link: https://hdl.handle.net/11104/0339292